Awarded Project: "Targeting Macrophages in Aging SIV-Infected Rhesus Macaques""

September 01, 2017
Targeting Macrophages in Aging SIV-Infected Rhesus Macaques

Dr. Marcelo Kuroda and Dr. Elizabeth Didier were awarded a four year grant from the National Heart, Lung, and Blood Institute at NIH.  The proposed research is relevant to public health for testing an intervention strategy to alleviate chronic
inflammation and disease associated with accelerated aging during HIV infection and antiretroviral therapy.
This study utilizes a nonhuman primate model of SIV infection, antiretroviral therapies, and aging to determine

Awarded Project: "Targeting Brain Macrophage Reservoirs of SIV during HAART"

September 25, 2015
Targeting Brain Macrophage Reservoirs of SIV during HAART

Dr. Marcelo Kuroda, in conjunction with the Eastern Virginia Medical School, received a five year award from the National Institute of Mental Health, NIH.  The overall goal of this proposal is to explore the role of long-lived brain perivascular macrophages (PVM) as the target cells for SIV infection in the central nervous system during the initial peak viremia and as a major reservoir of virus during chronic infection in the presence of HAART.