immunity

Article: "Optimal protection against Salmonella infection requires noncirculating memory"

October 17, 2018
Breakthrough in Designing a Better Salmonella Vaccine

UC Davis researchers announce in the Proceedings of the National Academy of Sciences this week a breakthrough in understanding which cells afford optimal protection against Salmonella infection—a critical step in developing a more effective and safe vaccine against a bacterium that annually kills an estimated one million people worldwide.

Awarded Project: "Immune Mechanisms Underlying Age-Related Neurodegeneration in HIV Infection"

September 30, 2018
Immune Mechanisms Underlying Age-Related Neurodegeneration in HIV Infection

Dr. Smita Iyer received a fiver year grant from the National Institute on Aging, NIH to study age-related neurodegeneration related to HIV infection.  An estimated 50% of HIV-infected patients on antiretroviral therapy develop neurocognitive disorders. This proposal uses robust powerful and complementary approaches to understand the immune mechanisms underlying age- related neurodegeneration during HIV infection.

Awarded Project: “Protective Humoral Immunity to Influenza Infection”

May 23, 2018
Protective Humoral Immunity to Influenza Infection

Nicole Baumgarth received a five year grant from the National Institute of Allergy and Infectious Diseases division of NIH to study “Protective Humoral Immunity to Influenza Infection”.  Antibody-mediated immunity generated by B lymphocytes is important for immune protection from infections. We are investigating a particular type of B cell response that we show to be induced after infection with influenza virus, but not after vaccination.