CRISPR

Awarded Project: "Bay Area CRISPR Reporters"

September 15, 2018
Bay Area CRISPR Reporters 

Dr. K.C. Kent Lloyd received a UC Multiple-Campus Award from the Office of the Director, NIH to participate with UCSF on Bay Area CRISPR Reporters.  A growing momentum and an ever-increasing body of evidence indicates that gene editing will become a standard treatment in therapeutic settings.  And although proof-of-principle and validation projects have demonstrated activity in cells and to some degree, in animal models, more work needs to be done in characterizing the activity of various gene  editing modalities.

Awarded Project: "Using CRISPR/Cas9 to decrease animal use by enhancing efficiency and reproducibility"

July 01, 2017
Using CRISPR/Cas9 to decrease animal use by enhancing efficiency and reproducibility

Joshua Wood was recently awarded a grant from the ACLAM Foundation, “Using CRISPR/Cas9 to decrease animal use by enhancing efficiency and reproducibility”.   The goal of this project is to reduce animal use by improving our ability to generate mutant mice by CRISPR/Cas9. The project investigates new tools and techniques such as electroporation and DNA oligos to increase our rates for deleting DNA and inserting DNA and thereby reducing the number of animals needed per mutant founder generated.