aging

Awarded Project: "Immune Mechanisms Underlying Age-Related Neurodegeneration in HIV Infection"

September 30, 2018
Immune Mechanisms Underlying Age-Related Neurodegeneration in HIV Infection

Dr. Smita Iyer received a fiver year grant from the National Institute on Aging, NIH to study age-related neurodegeneration related to HIV infection.  An estimated 50% of HIV-infected patients on antiretroviral therapy develop neurocognitive disorders. This proposal uses robust powerful and complementary approaches to understand the immune mechanisms underlying age- related neurodegeneration during HIV infection.

Awarded Project: "Targeting Macrophages in Aging SIV-Infected Rhesus Macaques""

September 01, 2017
Targeting Macrophages in Aging SIV-Infected Rhesus Macaques

Dr. Marcelo Kuroda and Dr. Elizabeth Didier were awarded a four year grant from the National Heart, Lung, and Blood Institute at NIH.  The proposed research is relevant to public health for testing an intervention strategy to alleviate chronic
inflammation and disease associated with accelerated aging during HIV infection and antiretroviral therapy.
This study utilizes a nonhuman primate model of SIV infection, antiretroviral therapies, and aging to determine