Using CRISPR/Cas9 to decrease animal use by enhancing efficiency and reproducibility
Joshua Wood was recently awarded a grant from the ACLAM Foundation, “Using CRISPR/Cas9 to decrease animal use by enhancing efficiency and reproducibility”. The goal of this project is to reduce animal use by improving our ability to generate mutant mice by CRISPR/Cas9. The project investigates new tools and techniques such as electroporation and DNA oligos to increase our rates for deleting DNA and inserting DNA and thereby reducing the number of animals needed per mutant founder generated. For more information please contact Joshua Wood.