Role of female genital mucosa associated CD4 T cells in vaccine-induced HIV susceptibility
Dr. Smita Iyer received a two year award. The majority of HIV infections by heterosexual transmission occur in women; understanding factors contributing to this increased risk is critical to prevent HIV infection in women and curb the global HIV/AIDS pandemic. This proposal uses robust complementary approaches and cutting-edge immunological tools to address this concern. Accomplishment of proposed goals will aid in designing interventions in women to prevent HIV infection.