Role of vaginal microbiome and metabolome in HIV vaccine efficacy
Dr. Smita Iyer was awarded a two year grant from the National Institute of Allergy and Infectious Diseases, NIH. A complete understanding of biological factors influencing vaccine efficacy is necessary to advance the development of an effective HIV vaccine. This proposal integrates robust cutting-edge approaches to understand these factors in the context of a funded pre-clinical study focused on enhancing HIV vaccine immunogenicity. Accomplishment of the proposed goals will advance rational design of HIV vaccines, which will significantly improve public health.