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The Center for Comparative Medicine’s Mission embraces the concept of “One Medicine” through interdisciplinary comparative medical research, teaching, and model development. Its research mission is to investigate the pathogenesis of human disease, using experimental animal models and naturally occurring animal diseases. CCM research programs facilitate its teaching mission of comparative medical training at the professional, graduate and post-graduate levels. CCM faculty expertise and programs in integrative biology provide animal model development, validation, and collaborative support to the general scientific community.

Latest News 

UC Davis Distinguished Emeritus/a Professor Award (11/30/2017) - World-renowned pathologist Dr. Robert Cardiff, a specialist in the diagnosis of breast and mammary cancer in both human and animal models, has been selected to receive the UC Davis Emeriti Association’s 2018 UC Davis Distinguished Emeritus Award. His distinguished career, based almost exclusively at UC Davis, has led to significant and meaningful effects on the […]
Wisdom Breast Cancer Study (10/11/2017) - Sandy Borowsky discusses the Wisdom Breast Cancer Study.  This study is hoping to enroll 100,000 California women age 40 and above to participate in a pragmatic (preference tolerated) randomized controlled trial design, where a participant can choose to have an annual mammogram, to have a personalized mammogram screen schedule based on their own risk or […]
The IRF4 gene regulatory module functions as a read-write integrator to dynamically coordinate T helper cell fate (9/27/2017) - Roger Sciammas, one of the newest CCM faculty members, recently published his first UCD research paper in the Journal, Immunity, “The IRF4 gene regulatory module functions as a read-write integrator to dynamically coordinate T helper cell fate”.   The authors (Veena Krishnamoorthy, Sunil Kannanganat, Mark Maienschein-Cline, Sarah L. Cook, Jianjun Chen, Neil Bahroos, Evelyn Sievert, Emily […]
CMV-vectored vaccine approaches to induce protective antibodies to HIV-1 Env (R21AI134618) (8/29/2017) - Peter Barry recently received a two year grant from the National Institute of Allergy and Infectious Diseases (NIAID) to study “CMV-vectored vaccine approaches to induce protective antibodies to HIV-1 Env” (R21AI134618).  This proposal is an exploratory investigation into approaches that will (1) promote antibody responses to rhesus cytomegalovirus (RhCMV)-vectored SIV vaccines in the face of […]
Using CRISPR/Cas9 to decrease animal use by enhancing efficiency and reproducibility (8/29/2017) - Joshua Wood was recently awarded a grant from the ACLAM Foundation, “Using CRISPR/Cas9 to decrease animal use by enhancing efficiency and reproducibility”.   The goal of this project is to reduce animal use by improving our ability to generate mutant mice by CRISPR/Cas9. The project investigates new tools and techniques such as electroporation and DNA oligos […]

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