The Center for Comparative Medicine’s Mission embraces the concept of “One Medicine” through interdisciplinary comparative medical research, teaching, and model development. Its research mission is to investigate the pathogenesis of human disease, using experimental animal models and naturally occurring animal diseases. CCM research programs facilitate its teaching mission of comparative medical training at the professional, graduate and post-graduate levels. CCM faculty expertise and programs in integrative biology provide animal model development, validation, and collaborative support to the general scientific community.

Latest News 

CMV-vectored vaccine approaches to induce protective antibodies to HIV-1 Env (R21AI134618) (8/29/2017) - Peter Barry recently received a two year grant from the National Institute of Allergy and Infectious Diseases (NIAID) to study “CMV-vectored vaccine approaches to induce protective antibodies to HIV-1 Env” (R21AI134618).  This proposal is an exploratory investigation into approaches that will (1) promote antibody responses to rhesus cytomegalovirus (RhCMV)-vectored SIV vaccines in the face of […]
Using CRISPR/Cas9 to decrease animal use by enhancing efficiency and reproducibility (8/29/2017) - Joshua Wood was recently awarded a grant from the ACLAM Foundation, “Using CRISPR/Cas9 to decrease animal use by enhancing efficiency and reproducibility”.   The goal of this project is to reduce animal use by improving our ability to generate mutant mice by CRISPR/Cas9. The project investigates new tools and techniques such as electroporation and DNA oligos […]
Comparative Medical Science Training Program (T32OD011147) (8/29/2017) - Nicole Baumgarth successfully renewed the National Institutes of Health “Comparative Medical Science Training Program” (T32OD011147).  This training program is to support graduate level research training for DVMs at the University of California, Davis, to address a national shortage of research-trained veterinarians. Veterinarians are needed to contribute to research into human health in many ways, including […]
A model to visualize CD4 T cell responses to non-pathogenic E. coli (8/29/2017) - Stephen McSorley recently received a two year grant from the National Institute of Allergy and Infectious Diseases (NIAID) to study “A model to visualize CD4 T cell responses to non-pathogenic E. coli”  (R21AI125228).  This grant will examine how host lymphocytes sense and regulate the composition of the normal intestinal microbiota. Understanding how non-pathogenic bacteria are […]
HIV Vaccine Developed Through Centers Collaboration: Moving towards human clinical trials (6/28/2016) - Over the past 6 years, Dr. Peter Barry’s lab at the Center for Comparative Medicine has been collaborating with Dr. Louis Picker and colleagues at the Oregon Health Science University (OHSU) to optimize a novel HIV vaccine.  The vaccine stems directly from research in Dr. Barry’s lab that has focused on the rhesus macaque model […]

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