Welcome to the Laboratory of Jay V. Solnick, MD, PhD
Helicobacter pylori is a gram-negative spiral bacterium that was discovered in 1981 by Barry Marshall and Robin Warren, who in 2005 were awarded the Nobel Prize in Physiology or Medicine for their discovery. H. pylori infects the gastric mucosa of approximately half the world’s population, and it is particularly common in developing countries. Although infection is asymptomatic in most cases, about 10% of those infected will develop peptic ulcer and 1-3% will develop gastric cancer, which is the second most common cause of cancer death in the world. The overall goal of the Solnick laboratory is to understand the pathogenic mechanisms by which H. pylori causes gastroduodenal diseases.