Anti-Neu staining in precancerous and cancerous tissue

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	Photomicrograph illustrating the distribution of anti-neu staining in a lactating mammary gland of a multiparous TGFalphaxneu female. Note the dense island of stain surrounded by non-staining mammary tissues.		Photomicrograph illustrating the distribution of anti-neu staining in an area of atypical hyperplasia in a female TGFalphaxneu mouse. While the whole mammary gland is hyperplastic the neu positive tissue has smaller lumina and larger cells.
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	Photomicrograph illustrating the distribution of anti-neu staining in the alveoli of a lactating neu mouse. Note that the stain is along the basolateral margins and that adjacent mammary gland does not stain. The non-staining alveolar cells have smaller nuclei and cells.		Photomicrograph illustrating the distribution of anti-neu staining in the tumor of a animal with the neu transgene. Note that the stain is along the cell membrane creating a honeycomb pattern.