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Illustrating low-grade (a,c) and high-grade (b,d) lesions of mammary intraepithelial neoplasms (MIN) found in the ducts
(a, b) and in the terminal ductules (c,d). Note the relative degree of nuclear pleomorphism and hyperchromasia. (a) is from a
MMTV/int-3 mouse.
(b) is from a C(3)1/SV40 tag mouse.
Figure (c) is from a MT/HGF mouse.
(d) is from a WAP/TGF a
mouse.
Use of figure and legend is courtesy of Oncogene (nature publishing group)
Cardiff et al, Oncogene (2000) 19, 968-988