Descriptors

DESCRIPTOR

DEFINITION

EXAMPLE
Glandular Tumor is composed of glands.
Acinar Tumor is composed of small glandular clusters with small lumens. While this is a subclass of glandular, it is very characteristic of MMTV-induced tumors.
Cribriform Tumor is composed of sheets or nests of cells forming lumens with round, punched out spaces..
Papillary Tumor has finger-like projections composed of epithelium covering a central fibrovascular core.
Solid Tumor is composed of solid sheets of epithelial cells with little or no glandular differentiation.
Squamous Tumors composed solely of squamous cells with or without keratinization, absence of glandular pattern.
Fibroadenoma Tumor is composed of a proliferation of both myxoid fibrous stroma and glands.
Adenomyoepithelioma Tumor is composed of myoepithelium and glands.
Adenosquamous Tumor has both glandular and squamous differentiation.
Not Otherwise Specified (NOS) Tumor does not have any of the other common descriptor patterns.

Use of table and images is courtesy of Oncogene (nature publishing group)
Cardiff et al, Oncogene (2000) 19, 968-988