Lobular Carcinoma in situ (LCIS)

     
  The diagnostic criteria for distinguishing "lobular" carcinoma in situ (LCIS) from ALH.
Dr. Roy Jensen, Vanderbilt
 

This low power image illustrates the diagnostic criteria for distinguishing LCIS from ALH. Notice how nearly all spaces are filled and distended by lobular neoplasia cells easily qualifying this case as LCIS.
Dr. Roy Jensen, Vanderbilt

 
     
  This high power image illustrates the diagnostic criteria for distinguishing LCIS from ALH. Notice how nearly all spaces are filled and distended by lobular neoplasia cells easily qualifying this case as LCIS
Dr. Roy Jensen, Vanderbilt
   
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  Histobank ID #1774
Low magnification image of a case of human LCIS.This image shows how the cells fill the terminal ductal lobular unit.
  Histobank ID #1775
Higher magnification image of a case of human LCIS.This image shows how the cells fill the terminal ductal lobular unit. Note that spindle shaped myoepithelial cells are present that would cause some experts to call this an atypical lobular hyperplasia grade IV.
 
40 x   40 x
  Histobank ID #1776
Highest magnification image of a case of human LCIS.This image shows how the cells fill the terminal ductal lobular unit. Note that spindle shaped myoepithelial cells are present that would cause some experts to call this an atypical lobular hyperplasia grade IV.
  Histobank ID #1777
Highest magnification image of a case of human LCIS.This image shows how the cells fill the terminal ductal lobular unit. Note that spindle shaped myoepithelial cells are present that would cause some experts to call this an atypical lobular hyperplasia grade IV.
 



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