Usual Hyperplasia of the Human Breast

Usual hyperplasia is a form of proliferative disease of the breast without atypia. This material was provided by Dr. Roy Jensen, Vanderbilt.

	This slide sets out the quantitative criteria. The adjectival designations mild, moderate and florid are quantitative assessments of extent.		These are the criteria for recognition.
	This slide illustrates the criteria for recognition of usual hyperplasia. The hallmark of usual hyperplasia or proliferative disease without atypia (PDWA) is variability. Each cell within the lesion has a different size, shape and orientation in comparison to adjacent cells. In addition, the secondary spaces are quite irregular in shape with a tendency to form small slit-like spaces.