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The low power image of the whole mount of the #4 mammary
fat pad from a retired breeder, multiparous FVB female mouse. Note the
smaller mass (squamous nodule) observed in the mammary gland The larger
nodule is the mammary lymph node. The squamous nodule is the most common
lesion found in the retired FVB female but they are relatively rare even
in this strain of mouse. Note that the rest of the mammary gland has many
side branches that end in relatively sharp terminal ends. This pattern
is typical of the aging, multiparous retired breeder
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The low power image of the whole mount of the #4 mammary
fat pad from a retired breeder, multiparous FVB female mouse. Note the
smaller mass (squamous nodule) observed in the mammary gland The larger
nodule is the mammary lymph node. The squamous nodule is the most common
lesion found in the retired FVB female but they are relatively rare even
in this strain of mouse. Note that the rest of the mammary gland has many
side branches that end in relatively sharp terminal ends. This pattern
is typical of the aging, multiparous retired breeder.
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The low power H&E stained image of a squamous nodule
observed in the mammary gland of the retired breeder multiparous FVB female
mouse. Note that the nodule is composed of both glandular and squamous
epithelium and that the stroma has a dense lymphocytic infiltrate. These
nodules are the most common lesions found in the retired FVB female but
they are relatively rare even in this strain of mouse. They are not thought
to be premalignant lesions.
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The higher power H&E stained
image of a squamous nodule observed in the mammary gland of the retired
breeder multiparous FVB female mouse. Note that the nodule is composed
of both glandular and squamous epithelium and that the stroma has a dense
lymphocytic infiltrate. These nodules are the most common lesions found
in the retired FVB female but they are relatively rare even in this strain
of mouse. They are not thought to be premalignant lesions.
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