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Summary Human Mouse

2.1.4.1. Anatomy of the aging lobule

With involution and post-menopausal aging, the TDLU undergoes atrophic changes As the woman ages, the lobule also undergoes characteristic atrophy. This set of images shows the typical changes.

1 x				4 x
	This breast slice shows complete atrophy of the TDLU but the branching duct tree will remain forever. From a 52 year old female with no breast cancer.		This breast slice shows the branching duct tree distended with secretion and a few remnants of lobules. The flowing tree of the young breast has become cacti in the desert.
	This breast slice illustrates the branching duct tree and a single TDLU with a delicate terminal duct. The microarchitecture of TDLU is recapitulated in pre-cancerous lesions and ductal carcinoma in-situ, as you will see later.