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Summary
Human Mouse



2.1.2.4. Structure of TDLU

63 x   250 x
  At even higher magnification the loose intralobular stroma is noted investing the ductules.   A single ductule cut transversely shows two cell types, an inner layer of secretory cells with abundant mitochondria and an outer sparse cell layer of myoepithelium with sparse cytoplasm. Epon imbedded toluidine blue stained.  
4000 x   100 x
  A single ductule is shown in this electronmicrograph. Fat droplets are noted in the apical cytoplasm of the secretory cells adjoining the lumen. The outer flattened myoepithelium contains abundant cytoplasmic filaments. The myoepithelium contracts when oxytoxin is released from the posterior pituitary gland during the early phase of nursing. Thus, the milk in the lobules is literally squeezed into the duct tree during nursing. This pituitary hormone is called the let down factor. Prolactin and endorphins are released into the blood stream from the pituitary by the let down factor stimulation. The nursing mother is thus experiencing extreme well being and contentment from her surge of endorphin hormone, the happiness hormone you could call it. The prolactin ensures nurturing behavior of the offspring and is the love hormone Nature has devised a pay-off in all facets of reproductive behavior.   Each ductule is invested with a basement membrane stained red with Periodic Acid Schiff (PAS).  



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Summary
Human Mouse