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Summary Human Mouse

2.1.2.3. Structure of the Terminal Ductal Lobular Unit (TDLU)

3.5 x
	A cluster of TDLU is seen at higher magnification from the previous slide. Note how the TDLU radiate around the small duct like spokes of a wheel. That architecture will allow the TDLU to expand in all directions during physiological hyperplasia of pregnancy and lactation.		This diagram shows the branching ducts (D) and the extralobular terminal ducts (ETD). From the intralobular part of the terminal duct (ITD) ductules (DTL) develop like test tubes as blindly ending structures. 30-50 ductules are present in each lobule (L) and can be likened to the delicate petals of a daisy. Note that the lobules have varying degrees of development that has been classified by Drs. Russo as LOBULE TYPE 1 - 3.
10 x				25 x
	The histologic appearance of several TDLU at low magnification.		At higher magnification note the sharp interphase between dense extralobuler connective tissue and each TDLU.