The Center for Comparative Medicine’s Mission embraces the concept of “One Medicine” through interdisciplinary comparative medical research, teaching, and model development. Its research mission is to investigate the pathogenesis of human disease, using experimental animal models and naturally occurring animal diseases. CCM research programs facilitate its teaching mission of comparative medical training at the professional, graduate and post-graduate levels. CCM faculty expertise and programs in integrative biology provide animal model development, validation, and collaborative support to the general scientific community.

Latest News 

260finallogo CRISPR Based Genome Editing Service (8/31/2015) - The UC Davis Mouse Biology Program (MBP) is happy to announce CRISPR-based genome editing (InDel, Exon Deletion [ExDel]) in murine embryonic stem (ES) cells and zygotes as a service for the academic scientific community.
NBaumgarth_small The Search for Persisters (8/13/2015) - Dr. Nicole Baumgarth was quoted in an article, “The Search for Persisters: Lyme disease–causing bacteria can outmaneuver antibiotics in vitro and manipulate the mouse immune system”, which was recently published by “TheScientist”.   The article discusses her research findings published in PLOS Pathogens.  Dr. Baumgarth’s research program investigates basic immunological mechanisms that regulate and control immunity […]
barry, peter A Sweet Treat Is a Clever Trick in Gauging Monkeys’ Health (7/21/2015) - The New York Times recently published an article, “A Sweet Treat Is a Clever Trick in Gauging Monkeys’ Health”, which describes how scientist here at UC Davis and within the PREDICT program were able to optimize techniques that had their beginnings here at the CCM and CNPRC while Tierra Smiley Evans was working in Dr. […]
barry, peter Impact of chronic viral infections and altered microbiota on HIV vaccine efficacy (7/16/2015) - CCM  Core Faculty member Dr. Peter Barry received funding from National Institute of Allergy and Infectious Diseases for HIV studies in microbiota, vaccines, and infant functional cures. DESCRIPTION (provided by applicant): Alterations in gut microbiota composition are found in chronic inflammatory non-infectious and infectious diseases including chronic HIV infection. Such changes may influence host immune […]
NBaumgarth_small Dr. Nicole Baumgarth featured in ScienceBlog (7/8/2015) - SVM researchers found that the bacteria that cause Lyme disease are able to trick an animal’s immune system into not launching a full-blown immune response or developing lasting immunity to the disease. Science Blog
NIH_logo Chris Miller, PhD Awarded a 5-year, $3.3 Million, NIH Research Project (R01) grant (6/25/2015) - Dr. Chris Miller was recently awarded a five year, $3.3 million, NIH Research Project (R01) grant, R01 AI118590 titled “How did a Vaccine Enhance HIV Acquisition?” This project seeks to understand how an Ad5 vectored HIV vaccine used in a STEP trial increased HIV infections and will provide us with valuable information that will help […]

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